• Toothbrush
  • Toothbrush
  • Toothbrush
  • Toothbrush
  • Toothbrush



Regenerate™ and Lissoni & Partners joined forces to create the state-of-the-art toothbrush, the ultimate combination of substance and style. Developed by the Enamel Science experts, Regenerate™ Toothbrush has 5904 ultra-thin, ultra-soft filaments for advanced enamel care*. Regenerate™ Toothbrush is made in Italy with antibacterial filaments** and regenerated plastic.

Regenerate™ Toothbrush has been designed with the minimalistic and timeless philosophy of Piero Lissoni, globally esteemed architect, art director and designer.
“I think working on a ‘finished’ object like a toothbrush is a little akin to designing a pencil: it’s almost impossible to design a new one, but we tried.
The first thing we did was to strip it down to the pure and essential nature of its function, taking away everything that was superfluous, any excess of ergonomics, design and material. We sought to design the toothbrush by taking advantage of its functional simplicity wherein, paradoxically, also lies its beauty.” Piero Lissoni, 03.06.2020
For over thirty years, Piero Lissoni has developed projects the world over in the fields of architecture, landscape and interior, as well as in product and graphic design. He has received a series of international awards, including the Good Design Award, the Red Dot Award and the Compasso d’Oro ADI.
*vs standard soft toothbrush
**infused with Silver Phosphate Glass to inhibit bacterial growth on filaments

How To Use

Brush your teeth with Regenerate™ Toothbrush for at least two to three minutes, twice a day. Thanks to its antibacterial filaments infused with Silver Phosphate Glass, Regenerate™ Toothbrush is able to inhibit the bacterial growth on filaments for 90 days*. It is recommended to change your toothbrush every 3 months to ensure a correct cleaning. For best results, use it with Regenerate™ Advanced Toothpaste to regenerate enamel mineral** reversing the early enamel erosion process.
*Relates to toothbrush bristles. Based on lab test. Bristles do not kill bacteria in mouth.
**Acts on early invisible stages of enamel erosion by restoring its mineral content and micro hardness with regular use. Clinically proven.

How It Works

Regenerate™ Toothbrush is gentle on tooth enamel and provides proven advanced enamel care compared to a standard soft toothbrush as demonstrated in an in-vitro test. The 5904 ultra-soft antibacterial filaments of just 101micron diameter are closely tufted in 41 holes to ensure effective yet silky brushing. The toothbrush handle is made with 93% regenerated plastic, at the forefront of sustainability in the industry. The plastic has been meticulously selected at the source and transformed into a new high quality design object. To close the loop and keep it cycling, the monocomponent toothbrush handle can be recycled subject to removal of the head - filaments are not recyclable yet.

REGENERATE Enamel Science™ Regime

REGENERATE Enamel Science™ Regime

The REGENERATE Enamel Science™ range fits effortlessly into your daily routine. The enamel mineral regenerating Advanced Toothpaste and Foaming Mouthwash can be used as daily dental care while the REGENERATE Enamel Science™ Advanced Serum is a monthly ritual. Combined use of the toothpaste and serum can regenerate 82% of enamel after 3 days¹.

¹Based on an in vitro test measuring enamel surface microhardness after 3 days’ combined use of Advanced Toothpaste and Advanced Enamel Serum.

REGENERATE Enamel Science™ Regime

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